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Galli lab

Cell-cycle control in multicellular organisms

Key Publications

Darmasaputra GS, Geerlings CC, Chuva de Sousa Lopes SM, Clevers H, Galli M. Binucleated human hepatocytes arise through late cytokinetic regression during endomitosis M phase. J Cell Biol. 223(8):e202403020 (2024).

Darmasaputra GS, van Rijnberk LM, Galli M. Functional consequences of somatic polyploidy in development. Development. 151(5):dev202392 (2024).

van Rijnberk LM, Barrull-Mascaró R, van der Palen RL, Schild ES, Korswagen HC, Galli M. Endomitosis controls tissue-specific gene expression during development. PLoS Biol. 20(5):e3001597 (2022).

Galli M & Morgan DO. Cell Size Determines the Strength of the Spindle Assembly Checkpoint during Embryonic Development. Dev Cell. 36(3):344-352 (2016).

Galli M, Muñoz J, Portegijs V, Boxem M, Grill SW, Heck AJ, van den Heuvel S. aPKC phosphorylates NuMA-related LIN-5 to position the mitotic spindle during asymmetric division. Nat Cell Biol. 13(9):1132-1138 (2011).

Galli M & van den Heuvel S. Determination of the Cleavage Plane in Early C. elegans Embryos. Annual Review of Genetics. 42:389-411 (2008).

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